News

19
May
2017

Two groups of Computation Institute researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory earned special awards from the office of the U.S. Secretary of Energy for addressing the global health challenges of Ebola and cancer.

04
May
2017

An international team of scientists including the Computation Institute has determined the 3-D atomic structures of more than 1,000 proteins that are potential targets for drugs and vaccines to combat some of the world’s most dangerous emerging and re-emerging infectious diseases.

01
May
2017

People have touted the potential of big data and computation in medicine for what feels like decades, promising more effective and personalized treatments, new research discoveries, and smarter clinical predictions. But only recently have these technologies made it to the clinic where they can actually improve patient care. At University of Chicago Medicine, several collaborations between physicians, researchers, and computational experts have produced such pioneering applications, from the pathology lab to the critical care wards.

Research

Conte Center logo

The overarching goal of our Center is to identify the genetic and environmental factors that underlie psychiatric disorders, including autism spectrum disorder, schizophrenia, bipolar disorder, depression, anxiety disorders, and child & adolescent psychopathology. Our team develops and applies drastically new mathematical and computational strategies to infer causal relationships among genetic variation, environmental variables and psychiatric phenotypes.

CSGID

CSGID applies state-of-the-art high-throughput (HTP) structural biology technologies to experimentally characterize the three dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

modENCODE project

The goal of the modENCODE project is to provide the biological research community with a comprehensive encyclopedia of genomic functional elements in the model organisms C. elegans and D. melanogaster. modENCODE is run as a Research Network and the consortium is formed by 11 primary projects, divided between worm and fly, spanning the domains of gene structure, mRNA and ncRNA expression profiling, transcription factor binding sites, histone modifications and replacement, chromatin structure, DNA replication initiation and timing, and copy number variation.

Researcher Spotlight